Description

Datura stramonium, known by the common names thorn apple, jimsonweed (jimson weed), devil's snare, or devil's trumpet, is a poisonous flowering plant of the nightshade family Solanaceae. It is a species belonging to the Datura genus and Daturae tribe. Its likely origin was in Central America, and it has been introduced in many world regions. It is an aggressive invasive weed in temperate climates and tropical climates across the world. D. stramonium has frequently been employed in traditional medicine to treat a variety of ailments. It has also been used as a hallucinogen (of the anticholinergic/antimuscarinic, deliriant type), taken entheogenically to cause intense, sacred or occult visions. It is unlikely ever to become a major drug of abuse owing to effects upon both mind and body frequently perceived as being highly unpleasant, giving rise to a state of profound and long-lasting disorientation or delirium (anticholinergic syndrome) with a potentially fatal outcome. It contains tropane alkaloids which are responsible for the psychoactive effects, and may be severely toxic.

Whole Genomes

Whole Genome Sequences & Annotations for Datura stramonium

• Datura stramonium gwh_assembly 378

S genes

Datura stramonium gwh_assembly 378 S genes

Query	Chromosome	Size(bp)	Coordinates	BLASTn Hit	BLASTn %ID	Domain
SLF18	Chr_1	215566500	159653742-159654878	Solanum tuberosum DM8.1, SLF18-2	82.7	F-box domain
SLF19Ψ	Chr_1	215566500	159892996-159891889	Solanum tuberosum DM8.1, SLF19	88.3	-
SLF13Ψ	Chr_1	215566500	183596560-183595382	Solanum lycopersicoides KU987621.1, SLF13	76.0	-
SLF16	Chr_1	215566500	210875950-210877119	Solanum tuberosum DM8.1, SLF16	84.2	F-box domain
SLF15	Chr_1	215566500	211690644-211689367	Solanum tuberosum DM8.1, SLF15	84.5	F-box domain

Downloads

The Datura stramonium S gene sequences are available in FASTA format.

CDS and Protein (FASTA file)

S-gene_Datura_stramonium

Publications

De-la-Cruz IM, Hallab A, Olivares-Pinto U, Tapia-López R, Velázquez-Márquez S, Piñero D, Oyama K, Usadel B, Núñez-Farfán J. Genomic signatures of the evolution of defence against its natural enemies in the poisonous and medicinal plant Datura stramonium (Solanaceae). Sci Rep. 2021 Jan 13;11(1):882. doi: 10.1038/s41598-020-79194-1.

Rajewski A, Carter-House D, Stajich J, Litt A. Datura genome reveals duplications of psychoactive alkaloid biosynthetic genes and high mutation rate following tissue culture. BMC Genomics. 2021 Mar 22;22(1):201. doi: 10.1186/s12864-021-07489-2.

Zhang F, Qiu F, Zeng J, Xu Z, Tang Y, Zhao T, Gou Y, Su F, Wang S, Sun X, Xue Z, Wang W, Yang C, Zeng L, Lan X, Chen M, Zhou J, Liao Z. Revealing evolution of tropane alkaloid biosynthesis by analyzing two genomes in the Solanaceae family. Nat Commun. 2023 Mar 15;14(1):1446. doi: 10.1038/s41467-023-37133-4.

Wu Y, Li D, Hu Y, Li H, Ramstein GP, Zhou S, Zhang X, Bao Z, Zhang Y, Song B, Zhou Y, Zhou Y, Gagnon E, Särkinen T, Knapp S, Zhang C, Städler T, Buckler ES, Huang S. Phylogenomic discovery of deleterious mutations facilitates hybrid potato breeding. Cell. 2023 May 25;186(11):2313-2328.e15. doi: 10.1016/j.cell.2023.04.008.